If you have high-risk factors for preeclampsia, start one low-dose aspirin tablet daily after 12 weeks of pregnancy, as prescribed

A few dozen yuan. Take the medicine daily as prescribed until delivery. The hard part is remembering every day.

The US Preventive Services Task Force gives this a Grade B recommendation: for women at high risk of preeclampsia, taking low-dose aspirin (81 mg per day) after week 12 of pregnancy can help prevent the condition. Preeclampsia is a hypertensive disorder unique to pregnancy. Results from multiple studies combined show the following outcomes, with 95% confidence intervals provided as ranges of reliability. The relative risk of preeclampsia drops to 0.85 (95% CI: 0.75 to 0.95, based on 16 studies), a reduction of roughly 15%. The relative risk of premature birth is 0.80 (95% CI: 0.67 to 0.95, based on 13 studies), a drop of about 20%. The relative risk of perinatal death — death occurring around the time of childbirth — is 0.79 (95% CI: 0.66 to 0.96, based on 11 studies), a reduction of roughly 21%. The relative risk of small-for-gestational-age infants or intrauterine growth restriction is 0.82 (95% CI: 0.68 to 0.99, based on 16 studies), a decrease of around 18%, meaning fetuses are less likely to be smaller than expected for their gestational age.

US Preventive Services Task Force (2021). Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication. https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication

The groups considered high risk include women who had preeclampsia in a prior pregnancy, those carrying twins or multiples, women with chronic hypertension, women with type 1 or type 2 diabetes prior to pregnancy, women with kidney disease, and women with autoimmune diseases such as systemic lupus erythematosus or antiphospholipid syndrome. Women not in these groups should not take aspirin on their own. This medication requires a doctor’s prescription; be sure to share your full medical history during prenatal checkups so your doctor can make an appropriate assessment. Most low-dose aspirin tablets sold in China are 100 mg enteric-coated tablets, and they must be taken strictly as directed by your doctor.